KMID : 0387820180250020170
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Clinical Pediatric Hematology-Oncology 2018 Volume.25 No. 2 p.170 ~ p.174
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Cytomegalovirus-Associated Severe Direct Antiglobulin Test Negative Hemolytic Anemia: A Case Report
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Hong Hyun-Jung
Cho Young-Hye Lim Jae-Young Yeom Jung-Sook Park Ji-Sook Park Eun-Sil Seo Ji-Hyun Woo Hyang-Ok Youn Hee-Shang
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Abstract
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Cytomegalovirus is a common virus that is mostly asymptomatic when infected, but rarely causes life-threatening hemolysis especially in immunocompromised children. We report a case of antiglobulin test negative severe hemolytic anemia caused by cytomegalovirus infection developed in an immune competent 9-year-old girl. The patient¡¯s hemoglobin level was 4.8 g/dL on the day of admission. The diagnosis was achieved by exclusion of other causes of hemolytic anemia and serological evidence of recent CMV infection. The patient was successfully treated with anti-viral agents and steroids resulting in recovery from anemia. Clinicians should consider cytomegalovirus infection in the differential diagnosis of hemolytic anemia in pediatric patients.
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KEYWORD
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Hemolytic anemia, Cytomegalovirus
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